Research Article
Phytochemical Analysis and Evaluation of Biological Activity of Lawsonia inermis Seeds Related to Alzheimer’s Disease
Table 2
AChE and BChE inhibitory activity of fractions and isolated compounds from L. inermis.
| Fractions | AChE IC50 (μg/mL) | BChE IC50 (μg/mL) | Compounds | AChE IC50 (μM) | BChE IC50 (μM) |
| PE | >500 | >500 | 1 | >100 | >100 | DCM | >500 | 113.47 ± 1.25 | 2 | >100 | 77.13 ± 0.01 | EtOAc | >500 | 124.90 ± 1.15 | 3 | >100 | >100 | MeOH | >500 | >500 | 4 | >100 | >100 | Donepezil | 0.03 ± 0.00 | 1.52 ± 0.10 | 5 | >100 | 72.20 ± 0.42 | | Donepezil | 0.08 ± 0.01 | 3.99 ± 0.27 |
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Data are expressed as mean ± SD (three independent experiments). |