Research Article

Phytochemical Analysis and Evaluation of Biological Activity of Lawsonia inermis Seeds Related to Alzheimer’s Disease

Table 2

AChE and BChE inhibitory activity of fractions and isolated compounds from L. inermis.

FractionsAChE IC50 (μg/mL)BChE IC50 (μg/mL)CompoundsAChE IC50 (μM)BChE IC50 (μM)

PE>500>5001>100>100
DCM>500113.47 ± 1.252>10077.13 ± 0.01
EtOAc>500124.90 ± 1.153>100>100
MeOH>500>5004>100>100
Donepezil0.03 ± 0.001.52 ± 0.105>10072.20 ± 0.42
Donepezil0.08 ± 0.013.99 ± 0.27

Data are expressed as mean ± SD (three independent experiments).