The Effects of Freshwater Clam (Corbicula fluminea) Extract on Activated Hepatic Stellate Cells

Figure 3

CE reduces the expression of a-SMA and collagen I in aHSCs. The aHSCs were exposed to CE (1 mg/ml) and palmitic acid (PA; 75 μM) for 5 days. Western blot analysis was performed to detect the levels of a-SMA, collagen I, and β-actin. A quantitative western blot analysis was used to calculate the a-SMA and collagen I values normalized to β-actin. The data are shown as the mean ± SD obtained from three independent experiments using isolated different batches of aHSCs. ^∗P < 0.05, ^∗∗P < 0.01, compared with the control.