Production of an Animal Model of Semi-Yin and Semi-Yang Syndrome with Diabetic Ulcers and Study of Its Pathological and Metabolic Features

Figure 2

Wounds on the back of rats. (a) Optimal dose and time at which a diabetic ulcer animal model with SYSY syndrome developed. The figure on the left shows wound healing at 8 days after oral administration of different doses of senna leaf. The figure on the right is the heat map of the changes of TCM syndromes of each rat after scoring according to the TCM syndromes rating scale of rats (Yang syndrome: pink < 15; SYSY syndrome: 15 < purple ≤ 30; Yin syndrome: black > 30). (b) Wound healing with different TCM syndromes. The figure on the left shows the wound healing at different time points after the successful establishment of animal models of TCM syndromes. The figure on the right is a heat map of the changes of TCM syndromes over time after the successful establishment of animal models of TCM syndromes. (c) Wound healing of different prescriptions corresponding to different TCM syndromes for treatment of SYSY. (d–f) Wound healing rate. , , and .

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