Review Article

Phytochemistry and Pharmacology of Thymus broussonetii Boiss

Table 2

Antibacterial effects of T. broussonetii.

Used partsExtractsUsed methodsTested strainsKey resultsReferences

Aerial partEssential oilAgar disk diffusion method
Broth microdilution method
Staphylococcus aureusФ = 42.67 ± 1.45 mm[26]
MIC = 0.2 μl/mL
MBC = 0.6 μl/mL
Escherichia coliФ = 29.33 ± 0.54 mm
MIC = 1.3 μl/mL
MBC = 1.3 μl/mL
Pseudomonas aeruginosaФ = 8.67 ± 1.20 mm
MIC = 20 μl/mL
MBC ≥ 80 μl/mL

Aerial partEssential oilAgar disc diffusion
Broth macrodilution method
Staphylococcus aureusФ = 35.00 ± 1.00 mm[13]
MIC = 0.9 mg/mL
MMC = 0.9 mg/mL
Bacillus subtilisФ = 49.67 ± 1.53 mm
MIC = 0.23 mg/mL
MMC = 0.23 mg/mL
Bacillus cereusФ = 48.67 ± 1.15 mm
MIC = 0.23 mg/mL
MMC = 0.23 mg/mL
Micrococcus luteusФ = 53.50 ± 1.00 mm
MIC = 0.12 mg/mL
MMC = 0.12 mg/mL
Escherichia coli 1 ATCC 25922Ф = 30.17 ± 1.00 mm
MIC = 0.90 mg/mL
MMC = 0.90 mg/mL
E. coli 2 CCMM B4Ф = 29.67 ± 1.53 mm
MIC = 0.90 mg/mL
MMC = 0.90 mg/mL
Enterobacter cloacaeФ = 27.33 ± 0.58 mm
MIC = 0.90 mg/mL
MMC = 0.90 mg/mL
Salmonella sp.Ф = 31.67 ± 1.53 mm
MIC = 0.90 mg/mL
MMC = 0.90 mg/mL
Staphylococcus aureusФ = 34.83 ± 1.04 mm
MIC = 0.91 mg/mL
MMC = 0.91 mg/mL
Bacillus subtilisФ = 49.00 ± 1.00 mm
MIC = 0.23 mg/mL
MMC = 0.23 mg/mL
Bacillus cereusФ = 47.33 ± 1.15 mm
MIC = 0.23 mg/mL
MMC = 0.23 mg/mL
Micrococcus luteusФ = 53.67 ± 1.15 mm
MIC = 0.12 mg/mL
MMC = 0.12 mg/mL
Escherichia coli 1 ATCC 25922Ф = 27.5 ± 1.53 mm
MIC = 0.91 mg/mL
MMC = 0.91 mg/mL
E. coli 2 CCMM B4Ф = 29.33 ± 1.53 mm
MIC = 0.91 mg/mL
MMC = 0.91 mg/mL
Enterobacter cloacaeФ = 23.33 ± 1.53 mm
MIC = 1.82 mg/mL
MMC = 1.82 mg/mL
Salmonella sp.Ф = 31.33 ± 1.53 mm
MIC = 0.91 mg/mL
MMC = 0.91 mg/mL

Aerial partEssential oilAgar diffusion methodBacillus subtilisФ = 33 ± 0.4 mm[33]
Staphylococcus aureusФ = 19 ± 0.8 mm
Salmonella sp.Ф = 19 ± 0.9 mm
Escherichia coliФ = 21 ± 0.1 mm
Vibrio choleraeФ = 40 ± 0.4 mm
Pseudomonas aeruginosaФ = 9 ± 0.1 mm

Aerial partEssential oilDisc diffusion methodMicrocystis aeruginosaФ = 90 ± 0.00 mm[17]
MIC = 0.047 mg/mL
MBC = 0.095 mg/ml
Aerial partEssential oilAgar diffusion methodStaphylococcus aureusNo measurable zone of inhibition[34]

Aerial partEssential oilAgar diffusion methodEscherichia coliNo measurable zone of inhibition[16]
MIC = 1%
Staphylococcus aureusMIC = 3%
Bacillus megateriumMIC = 4%