Synergistic Cytotoxicity between Elephantopus scaber and Tamoxifen on MCF-7-Derived Multicellular Tumor Spheroid

Figure 10

Gene expression of heat shock protein (HSP 105) in MCTS cultures treated by E. scaber, tamoxifen citrate, and their combinatorial treatment as measured by real-time quantitative PCR. E. scaber ethanol extract 60 μg/mL (ES60), tamoxifen citrate 3.125 μg/mL (TC3), and tamoxifen citrate 6.25 μg/mL (TC6). The results are expressed as fold change relative to the untreated control group. Data are presented as means ± SEM of three independent experiments. ∗Statistical significance () between control cells and treatment groups.