Synergistic Cytotoxicity between Elephantopus scaber and Tamoxifen on MCF-7-Derived Multicellular Tumor Spheroid

Figure 8

Caspase-8 and caspase-9 activities of MCF-7 cells in MCTS cultures after 4 days of treatment with E. scaber, tamoxifen citrate, and their combinatorial treatment. E. scaber ethanol extract 60 μg/mL (ES60), tamoxifen citrate 3.125 μg/mL (TC3), and tamoxifen citrate 6.25 μg/mL (TC6). The results are expressed as fold change relative to the untreated control group. Data are presented as means ± SEM of three independent experiments. ∗Statistical significance () between control cells and treatment groups.