Ethanolic Fruit Extract of Emblica officinalis Suppresses Neuroinflammation in Microglia and Promotes Neurite Outgrowth in Neuro2a Cells

Figure 3

Effect of EO crude fruit extract on the proinflammatory mediator IL-6 and TNF-α in BV2 and differentiated Neuro2a cells. Both BV2 and differentiated Neuro2a cells were treated with LPS (1 μg/mL) or EO crude fruit extract (0.5 and 1 μg/mL). After 24 h, the supernatant was collected, and ELISA assessed the IL-6 and TNF-α levels. (a) IL-6 level in BV2 cells; (b) IL-6 level in differentiated Neuro2a cells; and (c) TNF-α level in BV2 cells . (ANOVA; significant at and , compared with the LPS-treated group.)

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