Moxibustion Inhibits the Expression of Colonic NLRP3 through miR7/RNF183/NF-κB Signaling Pathway in UC Rats

Figure 2

Comparison of DAI, colonic morphology, pathological damage score, and the expression of IL-1β and NLRP3 proteins in colon: (a) change in DAI in each group; (b) comparison of DAI in the end of experiment; (c) colonic morphology under the microscope by HE staining (amplification × 200); (d) colonic pathological damage score in each group; (e) immunohistochemical staining of IL-1β protein in rat’s colon tissue in each group (amplification × 200); (f) IOD of IL-1β in each group; (g) immunohistochemical staining of NLRP3 protein in rat’s colon tissue in each group (amplification × 200); and (h) IOD of NLRP3 in each group. NG: normal group; MG: model group; MSMG: moxa-stick moxibustion group; CG: control group; DAI: disease activity index; IOD: integral optical density. Data expressed as mean ± SEM, n = 10 per group; vs. NG, and ; vs. MG, and ; and vs. MSMG, and .

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