In Vivo Antimalarial Activity of Polyalthia longifolia (Annonaceae) Leaf Extract and Assessment of Its Formulated Oral Dosage Forms

Table 2

Antiplasmodial four-day suppressive test of PLE in P. berghei passaged mice.

Groups	Dose (mg/kg)	Mean ± SEM
		Level of parasitaemia	% suppression
I	NI	0.00	NA
II	NC	23.74 ± 2.860	NA
III	12.5	10.02 ± 1.244	50.25
IV	100	9.30 ± 1.126	61.25
V	150	8.36 ± 1.187	65.17
VI	4.0 (Artesunate)	6.34 ± 0.715	73.58

Results are presented as mean ± SD; n = 6. . Values are compared to negative control; ^a values are compared to day 3. NI = normal control, NC = untreated group, and NA=not applicable.