In Vivo Antimalarial Activity of Polyalthia longifolia (Annonaceae) Leaf Extract and Assessment of Its Formulated Oral Dosage Forms
Table 3
Effect of PLE on hematological parameters of P. berghei passaged mice.
Groups
Hematological indices
PCV (%)
MCV(FL)
Hb(g/dL)
RBC (× 106/µL)
WBC (× 103/µL)
Plat. (× 103/µL)
I
58.4 ± 0.441a
57.2 ± 0.441a
12.2 ± 0.318a
10.2 ± 0.321a
16.3 ± 0.288a
1244 ± 2.082a
II
20.3 ± 0.665
41.0 ± 0.441
6.5 ± 0.321
4.95 ± 0.326
4.9 ± 0.321
102 ± 1.202
III
48.0 ± 0.416a
57.9 ± 0.466a
13.0 ± 0.272a
8.29 ± 0.300a
8.2 ± 0.202a
249 ± 1.764a
IV
50.1 ± 0.441a
58.8 ± 0.521a
12.4 ± 0.352a
8.52 ± 0.511a
9.9 ± 0.261a
693 ± 0.881a
V
50.4 ± 0.665a
56.4 ± 0.696a
13.2 ± 0.202a
8.94 ± 0.459a
10.3 ± 0.191a
824 ± 1.202a
VI
55.1 ± 0.665a
55.1 ± 0.521a
12.1 ± 0.405a
8.37 ± 0.385a
13.1 ± 0.208a
927 ± 1.528a
Results are presented as mean ± SD (n = 6) of triplicate determinations; mean values with superscript “a” in column are considered significant at . Plat. = platelets.