Research Article

In Vivo Antimalarial Activity of Polyalthia longifolia (Annonaceae) Leaf Extract and Assessment of Its Formulated Oral Dosage Forms

Table 3

Effect of PLE on hematological parameters of P. berghei passaged mice.

GroupsHematological indices
PCV (%)MCV(FL)Hb(g/dL)RBC (× 106/µL)WBC (× 103/µL)Plat. (× 103/µL)

I58.4 ± 0.441a57.2 ± 0.441a12.2 ± 0.318a10.2 ± 0.321a16.3 ± 0.288a1244 ± 2.082a
II20.3 ± 0.66541.0 ± 0.4416.5 ± 0.3214.95 ± 0.3264.9 ± 0.321102 ± 1.202
III48.0 ± 0.416a57.9 ± 0.466a13.0 ± 0.272a8.29 ± 0.300a8.2 ± 0.202a249 ± 1.764a
IV50.1 ± 0.441a58.8 ± 0.521a12.4 ± 0.352a8.52 ± 0.511a9.9 ± 0.261a693 ± 0.881a
V50.4 ± 0.665a56.4 ± 0.696a13.2 ± 0.202a8.94 ± 0.459a10.3 ± 0.191a824 ± 1.202a
VI55.1 ± 0.665a55.1 ± 0.521a12.1 ± 0.405a8.37 ± 0.385a13.1 ± 0.208a927 ± 1.528a

Results are presented as mean ± SD (n = 6) of triplicate determinations; mean values with superscript “a” in column are considered significant at . Plat. = platelets.