The Effect of Long-Term Duration Renal Replacement Therapy on Outcomes of Critically Ill Patients with Acute Kidney Injury: A Retrospective Cohort Study

Table 4

Baseline characteristics for critically ill patients at 60-day mortality.

Variables	Total (n = 506)	Death (n = 247)	Live (n = 259)	value
Age, years	64 (52, 74)	66 (54, 76)	61 (49, 70)	<0.001
Male, n (%)	306 (60.5%)	156 (63%)	150 (57.9%)	0.228
Heart rate, beats/min	106 ± 23	106 ± 23	106 ± 24	0.151
Mean arterial pressure, mmHg	56 (49, 63)	54 (47, 62)	57 (51, 64)	0.001
Respiratory rate, breath/min	28 (24, 34)	29 (24, 35)	28 (24, 33)	0.17
Creatinine admitted to ICU, mg/dL	2.9 (1.8, 4.4)	2.7 (1.8, 4.3)	3 (1.8, 4.5)	0.346
Creatinine in 24 hours before RRT initiation, mg/dL	4.2 (3, 5.5)	4 (2.9, 5.3)	4.3 (3.2, 5.8)	0.143
Duration of RRT, hours	105.5 (63.7, 188.3)	99 (63.7, 190)	110.3 (63.6, 186.9)	0.659
RRT modes, n (%)
CVVH	14 (2.7%)	7 (2.8%)	7 (2.7%)	0.928
CVVHD	160 (31.6%)	88 (35.6%)	72 (27.8%)	0.058
CVVHDF	223 (44.1%)	90 (36.5%)	133 (51.4%)	0.001
CVVH + CVVHD	88 (17.4%)	53 (21.5%)	35 (13.5%)	0.018
CVVH + CVVHDF	12 (2.4%)	6 (2.4%)	6 (2.3%)	0.934
CVVHD + CVVHDF	8 (1.6%)	3 (1.2%)	5 (1.9%)	0.519
Others	1 (0.2%)	0	1 (0.4%)	1
Main diagnosis class, n (%)
Cardiovascular	105 (20.8%)	53 (21.5%)	52 (20.1%)	0.702
Trauma	63 (12.4%)	31 (12.5%)	32 (12.4%)	0.947
Respiratory	20 (4%)	9 (3.6%)	11 (4.2%)	0.728
Infection	124 (24.5%)	61 (24.7%)	63 (24.3%)	0.923
Others	194 (38.3%)	93 (37.7%)	101 (39%)	0.756
Sepsis, n (%)	95 (18.8%)	48 (19.4%)	47 (18.1%)	0.711
Chronic kidney disease, n (%)	176 (34.8%)	84 (34%)	92 (35.5%)	0.721
Simplified Acute Physiology Score II	52.8 ± 14.6	54.4 ± 14.9	51.2 ± 14.2	0.555
SOFA	10 (7, 13)	11 (7, 13)	9 (7, 12)	0.07
Charlson comorbidity index	5 (3, 6)	5 (3, 6)	4 (2, 6)	0.007
Mechanical ventilation, n (%)	459 (90.7%)	226 (91.5%)	233 (90%)	0.552

RRT = renal replacement therapy; CVVH = continuous venovenous hemofiltration; CVVHD = continuous venovenous hemodialysis; CVVHDF = continuous venovenous hemodiafiltration.