The Effect of Long-Term Duration Renal Replacement Therapy on Outcomes of Critically Ill Patients with Acute Kidney Injury: A Retrospective Cohort Study

Table 5

Baseline characteristics for critically ill patients at 90-day mortality.

Variables	Total (n = 506)	Death (n = 268)	Live (n = 238)	value
Age, years	64 (52, 74)	66 (54, 76)	61 (48.5, 70)	<0.001
Male, n (%)	306 (60.5%)	167 (62.3%)	139 (58.4%)	0.369
Heart rate, beats/min	106 (90, 120)	106 (90, 119)	104 (88, 123)	0.956
Mean arterial pressure, mmHg	56 (49, 63)	54 (47, 62)	57 (51, 64)	0.006
Respiratory rate, breath/min	28 (24, 34)	29 (24, 35)	28 (24, 33)	0.101
Creatinine admitted to ICU, mg/dL	2.9 (1.8, 4.4)	2.6 (1.7, 4.3)	3 (1.9, 4.6)	0.07
Creatinine in 24 hours before RRT initiation, mg/dL	4.2 (3, 5.5)	4 (2.9, 5.3)	4.3 (3.2, 5.9)	0.053
Duration of RRT (h)	105.8 (63.7, 189.8)	99.5 (63.8, 190.3)	110.4 (63.2, 184.3)	0.792
RRT modes, n (%)
CVVH	14 (2.8%)	8 (3%)	6 (2.5%)	0.751
CVVHD	160 (31.6%)	93 (34.7%)	67 (28.2%)	0.114
CVVHDF	223 (44.1%)	98 (36.6%)	125 (52.5%)	<0.001
CVVH + CVVHD	88 (17.4%)	59 (22%)	29 (12.2%)	0.004
CVVH + CVVHDF	12 (2.4%)	6 (2.2%)	6 (2.5%)	0.835
CVVHD + CVVHDF	8 (1.5%)	3 (1.1%)	5 (2.1%)	0.484
Others	1 (0.2%)	1 (0.4%)	0	1
Main diagnosis class, n (%)
Cardiovascular	105 (20.8%)	59 (22%)	46 (19.3%)	0.702
Trauma	63 (12.4%)	36 (13.5%)	27 (11.4%)	0.478
Respiratory	20 (4%)	10 (3.7%)	10 (4.2%)	0.786
Infection	124 (24.5%)	64 (23.9%)	60 (25.2%)	0.729
Others	194 (38.3%)	99 (36.9%)	95 (39.9%)	0.492
Sepsis, n (%)	95 (18.8%)	51 (19%)	44 (18.5%)	0.876
Chronic kidney disease, n (%)	176 (34.8%)	94 (35.1%)	82 (34.5%)	0.884
Simplified Acute Physiology Score II	52.8 ± 14.6	54 ± 15	51.4 ± 14.2	0.524
SOFA	10 (7, 13)	10 (6, 13)	9 (7, 12)	0.113
Charlson comorbidity index	5 (3, 6)	5 (3, 6)	4 (2, 6)	0.002
Mechanical ventilation, n (%)	459 (90.7%)	246 (91.8%)	213 (89.5%)	0.375

RRT = renal replacement therapy; CVVH = continuous venovenous hemofiltration; CVVHD = continuous venovenous hemodialysis; CVVHDF = continuous venovenous hemodiafiltration.