Research Article

Yu-Ping-Feng Formula Exerts Antilung Cancer Effects by Remodeling the Tumor Microenvironment through Regulating Myeloid-Derived Suppressor Cells

Figure 7

The YPF formula downregulated the expression levels of MDSCs immunosuppressive-related genes and proliferation-related proteins in vitro. (a) RT-PCR was used to detect the expression levels of STAT3, iNOS, and Arg-1 mRNA in vitro. (b) Western blot was used to investigate the expression of MDSCs proliferation-related proteins p-STAT3, p-AKT, p-MEK, and p-ERK in vitro. All data were expressed as the mean ± SD from at least three independent experiments. , , and .
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