Evidence-Based Complementary and Alternative Medicine

Research Article

Hypoglycemic Effect of Calea urticifolia (Mill.) DC.

Table 5

Blood glucose levels under pyruvate curve.


Group/time (min)	Glucose levels in the pyruvate curve (mg/dL)
Group/time (min)	T0	T30	T60	T90	T120

Normoglycemic control	111 ± 4	118 ± 3	109 ± 2	105 ± 2	110 ± 4
Normoglycemic control	100%	106%	98%	95%	99%
Normoglycemic control + pyruvate	106 ± 4	169 ± 4^a,b	168 ± 7^a,b	151 ± 9^a,b	135 ± 9^a
Normoglycemic control + pyruvate	100%	159%	158%	142%	127%
Hyperglycemic control	190 ± 5	211 ± 6^a,b,c	204 ± 7^b,c	202 ± 10^b,c	199 ± 11^b,c
Hyperglycemic control	100%	111%	107%	106%	105%
Hyperglycemic control + pyruvate	196 ± 4	359 ± 12a	353 ± 13a	357 ± 19a	351 ± 17a
Hyperglycemic control + pyruvate	100%	182%	180%	182%	179%
Hyperglycemic + pyruvate + metformin, 500 mg/kg	211 ± 9	247 ± 16^a,c	193 ± 21^c	170 ± 24^c	152 ± 26^c
Hyperglycemic + pyruvate + metformin, 500 mg/kg	100%	117%	91%	81%	72%
Calea urticifolia (Mill.) DC., 41 mg/kg	195 ± 9	283 ± 16^a,c	302 ± 15^a,c	320 ± 13^a,c	320 ± 16^a,c
Calea urticifolia (Mill.) DC., 41 mg/kg	100%	145%	155%	164%	164%

The values represent the mean ± SEM; in the same row, a indicates statistically significant differences compared with time 0; in the same column, b indicates statistically significant differences compared with the normoglycemic control group and c indicates statistically significant differences compared with the hyperglycemic + pyruvate group; , n = 6.