Evidence-Based Complementary and Alternative Medicine

Research Article

The Efficacy of Rosa damascena on Liver Enzymes in Nonalcoholic Fatty Liver Disease: A Randomized Double-Blind Clinical Trial

Table 1

Amount variables at different times.


Variables	Group	Baseline mean ± SD	value	After 12 weeks mean ± SD	value	Percent change mean ± SD	value

BMI (kg/m²)	Rd	29.68 ± 3.66	0.064	28.46 ± 3.62	0.640	4.08 ± 3.96	0.102
	Placebo	30.05 ± 3.88		29.22 ± 3.85		2.71 ± 3.18
WC (cm)	Rd	103.69 ± 10.64	0.967	99.73 ± 10.01	0.424	3.75 ± 2.76	0.003
	Placebo	103.79 ± 8.89		101.52 ± 8.84		2.14 ± 2.71
ALT (IU/L)	Rd	69.05 ± 25.38	0.364	45.22 ± 19.45	0.262	31.52 ± 27.3	0.042
	Placebo	66.41 ± 25.24		50.22 ± 20.60		18.66 ± 29.62
AST (IU/L)	Rd	1.82 ± 38.38	0.937	30.19 ± 9.83	0.787	13.40 ± 33.86	0.166
	Placebo	37.44 ± 16.03		31.83 ± 12.60		11.33 ± 20.59
Systolic BP (mmHg)	Rd	125.47 ± 13.47	0.004	118.52 ± 11.33	0.18	5.33 ± 4.18	0.001
	Placebo	113.08 ± 11.70		113.47 ± 11.62		−0.395 ± 3.00
Diastolic BP (mmHg)	Rd	82.47 ± 12.17	0.97	82.47 ± 11.21	0.717	3.90 ± 7.78	0.001
	Placebo	82.60 ± 7.20		82.60 ± 7.51		0.22 ± 3.85
FBS (mg/dl)	Rd	108.85 ± 26.31	0.251	103.11 ± 26.77	0.713	3.12 ± 16.14	0.103
	Placebo	100.08 ± 25.12		103.94 ± 40.7		−3.42 ± 15.89
TG (mg/dl)	Rd	225.44 ± 121.16	0.112	186.29 ± 76.75	0.764	9.61 ± 35.11	>0.001
	Placebo	190.70 ± 100.29		184.47 ± 73.05		−3.67 ± 25.55
Cholesterol (mg/dl)	Rd	199.23 ± 30.81	0.214	167.47 ± 34.48	0.048	14.66 ± 18.95	>0.001
	Placebo	189.14 ± 35.29		184.11 ± 33.54		2.13 ± 8.01
HDL (mg/dl)	Rd	36.82 ± 7.22	0.961	41.85 ± 6.56	0.044	−14.94 ± 13.03	0.007
	Placebo	35.85 ± 4.06		39.20 ± 5.00		−9.8312.65
LDL (mg/dl)	Rd	112.91 ± 28.12	0.112	99.17 ± 28.66	0.208	19.97 ± 20.83	>0.001
	Placebo	112.08 ± 27.26		107.52 ± 12.60		3.28 ± 9.44
Platelet (mm³ × 10³)	Rd	257.86 ± 43.69	0.333	237.36 ± 43.99	0.768	7.53 ± 9.11	>0.002
	Placebo	240.40 ± 78.53		238.25 ± 54.21		0.05 ± 17.88
Urine SG	Rd	1019.61 ± 7.04	0.276	1025.79 ± 5.82	0.027	−0.60 ± .54	>0.001
	Placebo	1021.47 ± 8.86		1022.02 ± .75		−0.05 ± 5.17

BMI, body mass index; WC, waist circumference; ALT, alanine aminotransferase AST, aspartate aminotransferase; FBS, fasting blood sugar; TG, triglyceride, HDL, high-density lipoprotein, LDL, low-density lipoprotein, SG, specific gravity, minus means to increase; Mann–Whitney U test.