Research Article

Efficacy and Safety of Sahastara Remedy Extract Capsule in Primary Knee Osteoarthritis: A Randomized Double-Blinded Active-Controlled Trial

Table 3

Experimental results of Sahastara ethanolic extract and diclofenac.

DataFollow-upTreatment value
Sahastara (n = 32)Diclofenac (n = 31)

Walk 100 meters
 Knee pain levels: VAS (mm)Day 057.84 (2.19)54.61 (14.50)0.28m
Day 1446.12 (2.57)††41.09 (11.01)0.82m
Day 2836.46 (10.90)††29.77 (8.86)††0.01m
 100 meters walk (seconds)Day 0138.86 (40.38)130.41 (5.96)0.44m
Day 14129.37 (29.28)120.70 (4.14)0.11m
Day 28122.65 (26.46)111.51 (3.83)0.13m
WOMAC index scores
 Pain indexDay 08.25 (2.21)7.64 (3.02)0.23m
Day 145.93 (2.52)††5.61 (2.4)0.64m
Day 283.81 (2.05)††3.51 (1.94)††0.63m
 Stiffness indexDay 01.75 (1.81)1.69 (1.81)0.83m
Day 140.7 (1.34)0.57 (1.11)††0.44m
Day 280.09 (0.39)††0.09 (0.34)††0.64m
 Physical function indexDay 032.53 (8.8)31.66 (9.8)044m
Day 1424.87 (9.02)††24.87 (9.02)††0.19m
Day 2817.65 (7.78)††16.92 (7.6)††0.51m
 Total scoreDay 042.53 (1.88)40.06 (14.22)0.27m
Day 1432.96 (1.97)††28.61 (11.41)††0.21m
Day 2821.93 (1.75)††19.77 (8.75)††0.37m

Data represent mean (SD). ∗∗Statistical analysis. mMann–Whitney U test. For all within group statistical analysis: repeated measure ANOVA. Significant difference from day 0 within the group (); ††significant difference from day 0 within the group ().