Efficacy and Safety of Sahastara Remedy Extract Capsule in Primary Knee Osteoarthritis: A Randomized Double-Blinded Active-Controlled Trial
Table 3
Experimental results of Sahastara ethanolic extract and diclofenac.
Data
Follow-up
Treatment
value
Sahastara (n = 32)
Diclofenac (n = 31)
Walk 100 meters
Knee pain levels: VAS (mm)
Day 0
57.84 (2.19)
54.61 (14.50)
0.28m
Day 14
46.12 (2.57)††
41.09 (11.01)
0.82m
Day 28
36.46 (10.90)††
29.77 (8.86)††
0.01m
100 meters walk (seconds)
Day 0
138.86 (40.38)
130.41 (5.96)
0.44m
Day 14
129.37 (29.28)
120.70 (4.14)†
0.11m
Day 28
122.65 (26.46)†
111.51 (3.83)†
0.13m
WOMAC index scores
Pain index
Day 0
8.25 (2.21)
7.64 (3.02)
0.23m
Day 14
5.93 (2.52)††
5.61 (2.4)†
0.64m
Day 28
3.81 (2.05)††
3.51 (1.94)††
0.63m
Stiffness index
Day 0
1.75 (1.81)
1.69 (1.81)
0.83m
Day 14
0.7 (1.34)†
0.57 (1.11)††
0.44m
Day 28
0.09 (0.39)††
0.09 (0.34)††
0.64m
Physical function index
Day 0
32.53 (8.8)
31.66 (9.8)
044m
Day 14
24.87 (9.02)††
24.87 (9.02)††
0.19m
Day 28
17.65 (7.78)††
16.92 (7.6)††
0.51m
Total score
Day 0
42.53 (1.88)
40.06 (14.22)
0.27m
Day 14
32.96 (1.97)††
28.61 (11.41)††
0.21m
Day 28
21.93 (1.75)††
19.77 (8.75)††
0.37m
Data represent mean (SD). ∗∗Statistical analysis. mMann–Whitney U test. For all within group statistical analysis: repeated measure ANOVA. †Significant difference from day 0 within the group ();††significant difference from day 0 within the group ().