Network Pharmacology-Based Approach to Comparatively Predict the Active Ingredients and Molecular Targets of Compound Xueshuantong Capsule and Hexuemingmu Tablet in the Treatment of Proliferative Diabetic Retinopathy

Figure 4

Ingredient-target networks of different Chinese patent medicines. The triangles and circles represent potential therapeutic targets and active ingredients, respectively. (a) Network for the compound Xueshuantong capsule. The blue circles represent active ingredients in Radix salviae, the green circles represent active ingredients in Panax notoginseng, the yellow circles represent active ingredients in Hedysarum multijugum Maxim., the purple circles represent active ingredients in Figwort root, and the red circles represent active ingredients in multiple herbs. (b) Network for the Hexuemingmu tablet. The light blue circles represent active ingredients in Radix salviae, the bluish green circles represent active ingredients in Chuanxiong rhizoma, the light purple circles represent active ingredients in Radix paeoniae rubra, the yellow circles represent active ingredients in Gentianae radix et rhizoma, the dark blue circles represent active ingredients in Scutellariae radix, the light green circles represent active ingredients in Cassiae semen, the pink circles represent active ingredients in Chrysanthemi flos, the dark green circles represent active ingredients in Ecliptae herba, the light gray circles represent active ingredients in Equiseti hiemalis herba, the orange circles represent active ingredients in Fructus ligustri lucidi, the dark purple circles represent active ingredients in Pollen typhae, the dark gray circles represent active ingredients in Crataegus pinnatifida Bunge, the brown circles represent active ingredients in Prunellae spica, and the red circles represent active ingredients in multiple herbs.

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