Evidence-Based Complementary and Alternative Medicine / 2021 / Article / Tab 1 / Research Article
Molecular Composition and Antibacterial Effect of Five Essential Oils Extracted from Nigella sativa L. Seeds against Multidrug-Resistant Bacteria: A Comparative Study Table 1 Chemical constituents identified in the Nigella sativa L. essential oils of five countries.
Compounds Retention time India Saudi Arabia Morocco Syria France α -Phellandrene4.97 ± 0.00 10.58 ± 0.50 30.54 ± 1.01 29.64 ± 0.19 20.03 ± 0.56 4.31 ± 0.01 α -Pinene5.10 ± 0.00 6.29 ± 0.04 4.07 ± 0.06 1.07 ± 0.01 UC 5.27 ± 0.00 0.12 ± 0.01 0.06 ± 0.01 0.13 ± 0.00 0.14 ± 0.03 Camphene 5.36 ± 0.00 0.15 ± 0.02 0.15 ± 0.01 0.12 ± 0.03 0.18 ± 0.04 0.19 ± 0.03 UC 5.44 ± 0.00 0.05 ± 0.02 ± 0.11 ± 0.01 0.11 ± 0.06 0.20 ± 0.06 UC 5.67 ± 0.00 1.11 ± 0.04 β -Phellandrene5.74 ± 0.00 4.16 ± 0.07 4.42 ± 0.12 2.87 ± 0.00 2.39 ± 0.03 0.13 ± 0.00 β -Pinene5.82 ± 0.00 8.59 ± 0.10 9.77 ± 0.33 6.22 ± 0.01 4.53 ± 0.07 0.54 ± 0.04 β -Myrcene5.98 ± 0.00 0.17 ± 0.03 0.08 ± 0.02 0.15 ± 0.02 0.42 ± 0.08 0.42 ± 0.00 Ocimene 6.02 ± 0.00 0.31 ± 0.00 UC 6.04 ± 0.01 0.05 ± 0.01 0.33 ± 0.01 Pseudocumol 6.07 ± 0.00 0.11 ± 0.01 0.01 ± 0.00 0.32 ± 0.01 0.21 ± 0.01 0.50 ± 0.01 UC 6.18 ± 0.00 0.07 ± 0.04 0.02 ± 0.01 0.05 ± 0.00 0.26 ± 0.01 0.21 ± 0.00 α -Thujene6.24 ± 0.00 0.14 ± 0.03 0.07 ± 0.03 0.11 ± 0.03 (+)-4-Carene 6.26 ± 0.00 1.28 ± 0.11 UC 6.35 ± 0.00 0.10 ± 0.03 0.06 ± 0.02 0.20 ± 0.04 D-Limonene 6.39 ± 0.00 14.63 ± 1.42 α -Terpinen6.44 ± 0.00 1.67 ± 0.09 3.34 ± 0.17 2.25 ± 0.00 UC 6.45 ± 0.00 1.41 ± 0.29 UC 6.51 ± 0.00 0.06 ± 0.01 0.07 ± 0.01 ± ± β -Cymene6.56 ± 0.01 14.22 ± 0.08 12.31 ± 0.67 23.82 ± 0.04 14.61 ± 1.27 0.29 ± 0.00 UC 6.60 ± 0.00 0.27 ± 0.02 0.19 ± 0.01 UC 6.71 ± 0.00 0.23 ± 0.01 UC 6.77 ± 0.00 0.39 ± 0.05 Thujol 6.98 ± 0.00 0.05 ± 0.00 0.02 ± 0.00 0.02 ± 0.01 0.73 ± 0.10 0.63 ± 0.12 ɤ-Terpinene 7.14 ± 0.00 6.38 ± 0.34 1.89 ± 0.10 1.25 ± 0.06 5.77 ± 0.11 0.18 ± 0.07 UC 7.24 ± 0.00 0.44 ± 0.06 cis-β -Terpineol 7.29 ± 0.00 0.18 ± 0.01 0.17 ± 0.02 0.11 ± 0.01 0.48 ± 0.08 0.96 ± 0.12 Terpinolen 7.64 ± 0.00 0.37 ± 0.02 0.25 ± 0.03 0.15 ± 0.02 63 ± 0.08 0.58 ± 0.13 UC 7.68 ± 0.00 0.25 ± 0.02 3-Caranol 7.76 ± 0.00 0.28 ± 0.04 0.20 ± 0.06 Neodihydrocarveol 7.77 ± 0.00 3.34 ± 0.19 2.51 ± 0.03 1.63 ± 0.00 3.50 ± 0.25 0.52 ± 0.01 UC 8.04 ± 0.00 0.04 ± 0.01 0.04 ± 0.01 0.04 ± 0.01 0.31 ± 0.00 4-Caranol 8.14 ± 0.00 18.81 ± 0.57 14.27 ± 0.11 9.77 ± 0.08 9.85 ± 0.65 2.05 ± 0.03 UC 8.29 ± 0.00 0.07 ± 0.03 0.05 ± 0.00 0.03 ± 0.01 0.35 ± 0.03 0.49 ± 0.01 UC 8.45 ± 0.00 0.27 ± 0.01 0.43 ± 0.04 0.25 ± 0.03 0.46 ± 0.00 0.22 ± 0.03 UC 8.57 ± 0.00 0.04 ± 0.00 0.02 ± 0.00 0.01 ± 0.01 0.36 ± 0.07 0.47 ± 0.03 Limonene oxide 8.57 ± 0.00 0.66 ± 0.09 0.29 ± 0.07 Camphor 8.62 ± 0.00 0.08 ± 0.01 0.07 ± 0.02 0.05 ± 0.00 0.27 ± 0.04 0.96 ± 0.14 β -Cyclocitral8.75 ± 0.00 0.12 ± 0.02 0.05 ± 0.01 0.03 ± 0.00 0.17 ± 0.01 0.24 ± 0.10 UC 8.77 ± 0.00 0.94 ± 0.18 p-Cymen-8-ol 8.87 ± 0.00 0.24 ± 0.02 0.18 ± 0.01 Limonene epoxide 8.89 ± 0.00 1.02 ± 0.07 0.78 ± 0.01 0.52 ± 0.01 0.42 ± 0.04 0.45 ± 0.07 UC 8.99 ± 0.00 0.11 ± 0.00 0.04 ± 0.01 0.03 ± 0.01 0.40 ± 0.02 0.16 ± 0.02 4-Carvomenthenol 9.10 ± 0.00 3.35 ± 0.03 2.11 ± 0.01 1.44 ± 0.06 1.67 ± 0.03 0.47 ± 0.13 UC 9.19 ± 0.00 0.24 ± 0.02 0.20 ± 0.00 0.15 ± 0.01 0.12 ± 0.03 UC 9.25 ± 0.00 0.03 ± 0.00 0.02 ± 0.00 0.01 ± 0.00 0.32 ± 0.07 0.82 ± 0.04 UC 9.30 ± 0.00 0.11 ± 0.01 0.04 ± 0.00 0.03 ± 0.00 0.33 ± 0.03 UC 9.40 ± 0.00 0.10 ± 0.01 0.08 ± 0.03 0.07 ± 0.01 0.39 ± 0.02 β -Cyclocitral9.50 ± 0.00 2.10 ± 0.13 2.0 ± 0.05 1.39 ± 0.02 1.06 ± 0.01 0.24 ± 0.01 UC 9.54 ± 0.00 0.19 ± 0.01 0.24 ± 0.07 UC 9.55 ± 0.00 0.04 ± 0.00 0.02 ± 0.01 0.46 ± 0.02 0.22 ± 0.05 UC 9.74 ± 0.00 0.34 ± 0.04 0.13 ± 0.00 0.08 ± 0.00 0.35 ± 0.02 0.15 ± 0.01 Solanone 9.98 ± 0.00 0.42 ± 0.02 0.51 ± 0.03 Cuminal 10.08 ± 0.00 0.09 ± 0.01 0.24 ± 0.06 0.13 ± 0.02 0.19 ± 0.02 0.51 ± 0.03 Carvone 10.14 ± 0.00 0.18 ± 0.01 0.24 ± 0.01 0.010.15 ± 0.04 0.23 ± 0.01 1.01 ± 0.12 cis-Verbenol 10.19 ± 0.00 0.17 ± 0.03 0.40 ± 0.00 Thymoquinon 10.21 ± 0.00 0.32 ± 0.03 0.70 ± 0.10 0.50 ± 0.06 0.82 ± 0.11 UC 10.25 ± 0.00 0.08 ± 0.01 cis-Verbenol 10.27 ± 0.00 0.12 ± 0.01 0.08 ± 0.00 0.05 ± 0.01 0.19 ± 0.00 0.96 ± 0.01 UC 10.31 ± 0.00 0.02 ± 0.01 0.63 ± 0.14 Estragole 10.32 ± 0.00 20.22 ± 0.59 4-Carene 10.38 ± 0.00 0.24 ± 0.02 0.13 ± 0.01 0.09 ± 0.01 0.33 ± 0.08 0.64 ± 0.04 Carvacrol 10.49 ± 0.00 2.30 ± 0.09 1.22 ± 0.07 UC 10.71 ± 0.00 0.18 ± 0.04 0.28 ± 0.04 Bornyl acetate 10.76 ± 0.00 1.14 ± 0.09 0.84 ± 0.05 0.59 ± 0.05 1.18 ± 0.04 UC 10.86 ± 0.00 0.09 ± 0.01 0.03 ± 0.00 ± 0.12 ± 0.01 Thymol 10.92 ± 0.00 4.64 ± 0.01 8.39 ± 0.39 7.00 ± 0.03 ± UC 11.14 ± 0.00 0.07 ± 0.03 0.02 ± 0.00 0.04 ± 0.00 0.18 ± 0.03 UC 11.30 ± 0.00 0.04 ± 0.01 0.02 ± 0.01 UC 11.55 ± 0.00 0.20 ± 0.01 Cedrene 11.60 ± 0.00 0.22 ± 0.01 β -Terpinyl acetate11.65 ± 0.00 0.10 ± 0.03 0.02 ± 0.00 0.18 ± 0.02 ± α -Longipinene11.78 ± 0.00 2.23 ± 0.09 0.29 ± 0.02 0.18 ± 0.01 1.22 ± 0.05 0.51 ± 0.10 UC 12.05 ± 0.00 0.06 ± 0.02 0.15 ± 0.03 Patchoulene 12.07 ± 0.00 4.00 ± 0.05 3.29 ± 0.00 Columbin 12.11 ± 0.00 0.14 ± 0.02 0.05 ± 0.01 0.02 ± 0.00 UC 12.16 ± 0.00 0.04 ± 0.01 0.02 ± 0.00 0.12 ± 0.04 0.42 ± 0.00 Aromadendrene 12.22 ± 0.00 0.29 ± 0.04 0.69 ± 0.10 UC 12.31 ± 0.00 0.04 ± 0.01 0.02 ± 0.01 0.01 ± 0.00 0.18 ± 0.01 0.19 ± 0.05 UC 12.41 ± 0.00 0.06 ± 0.01 0.02 ± 0.00 0.04 ± 0.02 0.18 ± 0.00 0.24 ± 0.01 UC 12.51 ± 0.00 0.06 ± 0.02 Longicyclene 12.56 ± 0.00 0.31 ± 0.02 0.02 ± 0.00 ± 0.00 β -Chamigrene12.62 ± 0.00 9.54 ± 0.49 1.54 ± 0.08 1.14 ± 0.02 UC 12.68 ± 0.00 0.02 ± 0.01 0.13 ± 0.03 0.19 ± 0.03 α -Bisabolene12.77 ± 0.00 0.18 ± 0.02 0.06 ± 0.01 0.03 ± 0.01 0.21 ± 0.04 0.62 ± 0.00 Longifolene-(V4) 12.91 ± 0.00 2.61 ± 0.02 UC 12.99 ± 0.00 1.20 ± 0.07 UC 13.00 ± 0.00 0.05 ± 0.01 0.04 ± 0.02 0.01 ± 0.00 0.25 ± 0.02 0.20 ± 0.09 Methyl undecyl ketone 13.07 ± 0.00 1.51 ± 0.11 0.79 ± 0.04 UC 13.12 ± 0.01 0.03 ± 0.01 0.04 ± 0.01 0.01 ± 0.00 0.75 ± 0.09 UC 13.17 ± 0.00 0.87 ± 0.07 0.47 ± 0.07 a-Curcumene 13.28 ± 0.00 0.11 ± 0.03 0.03 ± 0.00 0.02 ± 0.00 0.25 ± 0.02 b-Sesquiphellandrene 13.38 ± 0.00 0.36 ± 0.01 UC 13.49 ± 0.00 0.06 ± 0.01 0.05 ± 0.01 0.03 ± 0.02 0.32 ± 0.08 2-Tridecanone 13.57 ± 0.00 0.38 ± 0.02 0.11 ± 0.02 0.07 ± 0.02 1.13 ± 0.03 1.40 ± 0.14 UC 13.64 ± 0.00 0.07 ± 0.02 0.04 ± 0.01 0.02 ± 0.01 0.19 ± 0.02 1.14 ± 0.04 β -Bisabolene13.83 ± 0.00 0.17 ± 0.03 0.04 ± 0.01 0.03 ± 0.01 0.14 ± 0.08 0.15 ± 0.01 UC 13.99 ± 0.00 0.06 ± 0.01 0.04 ± 0.01 0.02 ± 0.00 ± 0.23 ± 0.07 Isoledene 14.15 ± 0.00 0.15 ± 0.02 0.03 ± 0.01 0.01 ± 0.01 0.16 ± 0.01 0.37 ± 0.04 UC 14.40 ± 0.00 0.04 ± 0.00 0.04 ± 0.01 0.02 ± 0.01 0.15 ± 0.04 0.92 ± 0.13 UC 14.72 ± 0.00 0.04 ± 0.01 0.02 ± 0.00 0.13 ± 0.03 0.79 ± 0.06 a-Pentylcinnamaldehyde 14.78 ± 0.00 0.47 ± 0.08 UC 14.85 ± 0.00 0.28 ± 0.03 0.13 ± 0.03 0.07 ± 0.02 0.15 ± 0.06 1.21 ± 0.03 Ar-tumerone 15.05 ± 0.00 ± ± ± ± 0.55 ± 0.04 UC 15.06 ± 0.00 0.22 ± 0.03 0.10 ± 0.01 0.06 ± 0.00 0.24 ± 0.02 0.38 ± 0.10 UC 15.17 ± 0.00 0.07 ± 0.01 0.02 ± 0.01 0.05 ± 0.05 0.18 ± 0.06 1.30 ± 0.14 Curlone 15.41 ± 0.00 0.67 ± 0.06 UC 15.62 ± 0.00 0.09 ± 0.02 0.05 ± 0.01 0.01 ± 0.00 0.21 ± 0.10 2.38 ± 0.01 UC 15.87 ± 0.00 0.15 ± 0.03 0.06 ± 0.02 0.05 ± 0.02 1.09 ± 0.04 UC 16.04 ± 0.00 0.09 ± 0.02 0.02 ± 0.01 UC 16.09 ± 0.00 0.11 ± 0.02 0.05 ± 0.01 Globulol 16.15 ± 0.00 0.34 ± 0.04 0.05 ± 0.00 0.03 ± 0.01 0.13 ± 0.04 1.42 ± 0.00 Palmitic acid 16.55 ± 0.00 0.16 ± 0.01 UC 16.64 ± 0.00 0.21 ± .05 0.15 ± 0.03 0.06 ± 0.02 0.27 ± 0.03 2.09 ± 0.00 UC 16.88 ± 0.00 0.09 ± 0.02 0.03 ± 0.01 0.02 ± 0.00 0.23 ± 0.08 Biformene 18.18 ± 0.02 1.07 ± 0.05 UC 18.24 ± 0.00 4.16 ± 0.17 UC 18.34 ± 0.01 1.85 ± 0.06 7,10-Octadecadienoic acid 19.21 ± 0.01 0.55 ± 0.04 UC 19.39 ± 0.00 2.97 ± 0.03
