Network Pharmacology-Based Strategy for Predicting Active Ingredients and Potential Targets of Coptis chinensis Franchin Polycystic Ovary Syndrome

Table 1

Active ingredients of Coptis chinensis selected from TCMSP.

Molecular number	Active ingredients	Chemical formula	OB %	DL
MOL001454	Berberine	C^20H^18ClNO^4	36.86	0.19
MOL013352	Obacunone	C^26H^30O^7	43.29	0.31
MOL002894	Berberrubine	C^19H^16ClNO^4	35.74	0.24
MOL002897	Epiberberine	C^20H^17NO^5	43.09	0.19
MOL002903	(R)-Canadine	C^20H^21NO^4	55.37	0.2
MOL002904	Berlambine	C^20H^17NO^5	36.68	0.28
MOL002907	Corchoroside A	C^29H^42O^9	104.95	0.29
MOL000622	Magnograndiolide	C^15H^22O^4	63.71	0.3
MOL000762	Palmidin A	C^30H^22O^8	35.36	0.39
MOL000785	Palmatine	C^21H^24ClNO^5	64.6	0.13
MOL000098	Quercetin	C^15H^10O^7	46.43	0.38
MOL001458	Coptisine	C^19H^14ClNO^4	30.67	0.26
MOL002668	Worenine	C^20H^16NO^4+	45.83	0.27
MOL008647	Moupinamide	C^18H^19NO^4	86.71	0.33

The table lists the effective ingredients of Coptis chinensis obtained in the TCMSP database with OB ≥ 30 and DL ≥ 0.18 as the screening conditions. TCMSP: TCM systems pharmacology database and analysis platform. OB: Oral bioavailability. DL: Drug-like.