Antioxidant, Anti-Inflammatory, and Cytotoxic Properties and Chemical Compositions of Filipendula palmata (Pall.) Maxim.

Table 5

Antiproliferative activities of compounds against four tumor cell lines (IC₅₀, µg/mL).

Compound	The IC50 of antiproliferative activity (μg/mL)
	MCF-7	HeLa	4T1	A549
Doxorubicin	65.61 ± 2.25	12.52 ± 1.02	152.22 ± 7.25	10.72 ± 1.11
8	96.58 ± 3.69	46.21 ± 3.33	205.15 ± 8.77	39.88 ± 2.05
9	125.66 ± 4.77	50.84 ± 4.21	181.27 ± 6.99	45.55 ± 1.37
10	68.13 ± 3.54	13.22 ± 1.33	172.22 ± 8.12	29.09 ± 1.22
11	72.32 ± 2.25	16.55 ± 1.25	195.66 ± 10.21	26.52 ± 1.54
12	75.65 ± 3.21	18.17 ± 1.63	230.11 ± 12.11	33.55 ± 1.62
13	80.25 ± 4.12	19.22 ± 2.30	245.22 ± 10.69	52.21 ± 1.39
14	81.36 ± 2.66	22.36 ± 1.89	285.66 ± 9.87	46.36 ± 1.77
15	83.64 ± 3.10	22.57 ± 2.06	>400	55.30 ± 2.12
16	110.95 ± 6.21	38.24 ± 2.55	235.66 ± 13.25	39.55 ± 1.25
17	85.66 ± 4.12	21.21 ± 1.78	227.55 ± 11.21	40.75 ± 2.36
18	88.63 ± 2.12	23.77 ± 2.13	265.22 ± 16.32	29.36 ± 0.25
19	86.49 ± 3.82	23.84 ± 2.11	301.11 ± 18.12	35.32 ± 1.89
20	82.34 ± 2.65	20.96 ± 1.21	>400	49.87 ± 1.92
21	84.47 ± 3.33	23.65 ± 1.84	322.02 ± 16.14	38.65 ± 2.13
22	85.11 ± 3.58	22.31 ± 1.64	275.22 ± 11.01	42.09 ± 1.69
23	89.65 ± 2.36	24.33 ± 2.12	226.22 ± 13.21	51.25 ± 2.17
24	84.29 ± 3.64	21.95 ± 1.76	352.21 ± 15.62	50.12 ± 1.99

vs. control group; vs. model group. The values are means ± standard errors of the experiment carried out in triplicates.