Network Pharmacology Strategy to Investigate the Pharmacological Mechanism of Siwu Decoction on Primary Dysmenorrhea and Molecular Docking Verification

<table class="table-group" id="tab2"><tr><td><table class="table"><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr class="thead"><td class="align_left">Gene symbol</td><td class="align_center">EntrezID</td></tr><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr><td class="align_left">PGR</td><td class="align_center">5241</td></tr><tr><td class="align_left">PTGS1</td><td class="align_center">5742</td></tr><tr><td class="align_left">PTGS2</td><td class="align_center">5743</td></tr><tr><td class="align_left">ADRB2</td><td class="align_center">154</td></tr><tr><td class="align_left">OPRM1</td><td class="align_center">4988</td></tr><tr><td class="align_left">BAX</td><td class="align_center">581</td></tr><tr><td class="align_left">CASP3</td><td class="align_center">836</td></tr><tr><td class="align_left">PPARG</td><td class="align_center">5468</td></tr><tr><td class="align_left">AKT1</td><td class="align_center">207</td></tr><tr><td class="align_left">MMP1</td><td class="align_center">4312</td></tr><tr><td class="align_left">CYP3A4</td><td class="align_center">1576</td></tr><tr><td class="align_left">CYP1A1</td><td class="align_center">1543</td></tr><tr><td class="align_left">CYP1B1</td><td class="align_center">1545</td></tr><tr><td class="align_left">ALOX5</td><td class="align_center">240</td></tr><tr><td class="align_left">GSTP1</td><td class="align_center">2950</td></tr><tr><td class="align_left">AHR</td><td class="align_center">196</td></tr><tr><td class="align_left">SLC2A4</td><td class="align_center">6517</td></tr><tr><td class="align_left">GSTM1</td><td class="align_center">2944</td></tr><tr><td class="align_left">ESR1</td><td class="align_center">2099</td></tr><tr><td class="align_left">KDR</td><td class="align_center">3791</td></tr><tr><td class="align_left">ESR2</td><td class="align_center">2100</td></tr><tr><td class="align_left">AKR1B1</td><td class="align_center">231</td></tr><tr><td class="align_left">PLAU</td><td class="align_center">5328</td></tr><tr class="table-tr"><td colspan="2"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>Gene symbols and entrezIDs of the active target genes.</div>

Evidence-Based Complementary and Alternative Medicine

tab2

Table 2

Table 2: Network Pharmacology Strategy to Investigate the Pharmacological Mechanism of Siwu Decoction on Primary Dysmenorrhea and Molecular Docking Verification 

Table 2 | Network Pharmacology Strategy to Investigate the Pharmacological Mechanism of Siwu Decoction on Primary Dysmenorrhea and Molecular Docking Verification 