Antihypertensive Effects of the Vitex cienkowskii (Verbenaceae) Stem-Bark Extract on L-NAME-Induced Hypertensive Rats

Figure 2

Effects of the methanol/methylene chloride extract of V. cienkowskii on body weight. Each bar represents the mean ± SEM; n = 5;  < 0.05;  < 0.01 significant differences compared to control (rats receiving distilled water); ^$ < 0.05; ^$$ < 0.01 significant differences compared to hypertensive control (rats receiving L-NAME only); L-NAME + CAPT: rats treated with L-NAME and captopril at the dose of 25 mg/kg; L-NAME + MMVC (200 mg/kg): rats treated with L-NAME and plant extract (MMVC) at the dose of 200 mg/kg; L-NAME + MMVC (400 mg/kg): rats treated with L-NAME and plant extract (MMVC) at the dose of 400 mg/kg; Week 0: week before the 1^st week of treatment; Week 1–Week 4: the 1^st to 4^th week of treatment.