Antihypertensive Effects of the Vitex cienkowskii (Verbenaceae) Stem-Bark Extract on L-NAME-Induced Hypertensive Rats

Figure 3

Effects of the methanol/methylene chloride extract of V. cienkowskii on food (a) and water intake (b). Each bar represents the mean ± SEM; n = 5;  < 0.05;  < 0.01 significant differences compared to control (rats receiving distilled water); ^$$ < 0.01 significant difference compared to hypertensive control (rats receiving L-NAME only); L-NAME + CAPT: rats treated with L-NAME and captopril at the dose of 25 mg/kg; L-NAME + MMVC (200 mg/kg): rats treated with L-NAME and plant extract (MMVC) at the dose of 200 mg/kg; L-NAME + MMVC (400 mg/kg): rats treated with L-NAME and plant extract (MMVC) at the dose of 400 mg/kg; g or mL/100 g of body weight: quantity consumed in g or mL per week per 100 g of body weight; Week 0: week before the 1^st week of treatment; Week 1–Week 4: the 1^st to 4^th week of treatment.

(a)

(b)