The Exploration of Novel Pharmacophore Characteristics and Multidirectional Elucidation of Structure-Activity Relationship and Mechanism of Sesquiterpene Pyridine Alkaloids from <i>Tripterygium</i> Based on Computational Approaches

<div>Structures of sesquiterpene pyridine alkaloids from <i>Tripterygium</i>: (a) 55 sesquiterpene pyridine alkaloids of which pyridine ring 2′, 3′ position or 3′, 4′ position are connected to macrocyclic; (b) dihydro-<i>β</i>-agarofuran sesquiterpenoid moiety; (c) 2-(carboxyalkyl) nicotinic acid moiety; (d) macrocyclic dilactone skeleton from <i>Tripterygium</i>.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 1: The Exploration of Novel Pharmacophore Characteristics and Multidirectional Elucidation of Structure-Activity Relationship and Mechanism of Sesquiterpene Pyridine Alkaloids from <i>Tripterygium</i> Based on Computational Approaches 

Figure 1 | The Exploration of Novel Pharmacophore Characteristics and Multidirectional Elucidation of Structure-Activity Relationship and Mechanism of Sesquiterpene Pyridine Alkaloids from Tripterygium Based on Computational Approaches 