The Exploration of Novel Pharmacophore Characteristics and Multidirectional Elucidation of Structure-Activity Relationship and Mechanism of Sesquiterpene Pyridine Alkaloids from Tripterygium Based on Computational Approaches

Figure 7

Schematic contact map of seven alkaloids and the FDFT1 (1.44 Å, PDB code 6PYJ) pocket: (a) hypoglaunine C (docking scores 112.66); (b) wilfornine G (docking scores 98.85); (c) euojaponine I (docking scores 107.11); (d) wilfordinine G (docking scores 120.87); (e) alatusinine (docking scores 97.51); (f) wilfordinine F (docking scores 109.26); (g) wilforjine (docking scores 120.19).

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