Chemical Group Profiling, In Vitro and In Silico Evaluation of Aristolochia ringens on α-Amylase and α-Glucosidase Activity

Table 3

Pharmacokinetic properties of dianoside G, trilobine, and acarbose.

Properties	Acarbose	Dianoside G	Trilobine
Molecular formula	C25H43NO18	C48H76O20	C35H34N2O5
Molecular weight (g/mol)	645.60	973.11	562.65
Bioavailability score	0.17	0.11	0.55
Water solubility	High	Moderate	Poor
Lipophilicity (ilogP)	0.63	2.49	4.66
GIT absorption	Low	Low	High
BBB-permeability	No	No	No
Hydrogen bond acceptors	19	20	7
Hydrogen bond donors	14	12	1
Lipinski’s rule	No	No	Yes
Synthetic accessibility	7.34	9.91	6.60