Quyu Shengxin Decoction Alleviates DSS-Induced Ulcerative Colitis in Mice by Suppressing RIP1/RIP3/NLRP3 Signalling

Figure 7

The levels of Drp1 (a) in the DSS group, 5-ASA group, SX group, and QY group were significantly higher than those in the control group (). The level of Drp1 in the QYSX group was significantly lower than that in the DSS group, 5-ASA group, SX group, and QY group. The level of Drp1 in the 5-ASA group was also lower than that in the DSS group (). The levels of caspase-1 (b) in the DSS group, QYSX group, 5-ASA group, SX group, and QY group were significantly higher than those in the control group. The caspase-1 level in the QYSX group was significantly lower than that in the DSS group, 5-ASA group (^&), SX group (^&), and QY group (^&). The levels of FIS1 (c) in the DSS group, SX group, and QY group were significantly higher than those in the control group (). The FIS1 level in the QYSX group was significantly lower than those in the DSS group, SX group, and QY group (^&&), and the FIS1 level in the 5-ASA group was also lower than that in the DSS group (^&&). The level of LC3a/b (d) in the DSS group, 5-ASA group, SX group, and QY group was significantly higher than that in the control group. The value in the QYSX group was significantly lower than that in the DSS group (^&).

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