Research Article

Nardosinone Alleviates Parkinson’s Disease Symptoms in Mice by Regulating Dopamine D2 Receptor

Figure 2

Nardosinone reverses rotenone-induced motor and cognitive impairment in mice. The open field motion trajectories of control group (a), ROT (subcutaneously injected with 3 μg/g/day body weight of rotenone) group (b), and ROT + NAR (intraperitoneal injection of 80 μg/g/day nardosinone) group (c). (d) Open field movement distance of mice in each group. (e) Number of the active avoidance of shuttle box in each group (results are expressed as (n = 6); and versus control group; versus ROT group).
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