The Antioxidant, Anti-Inflammatory, Pathological, and Behavioural Effects of Medicago sativa L. (Alfalfa) Extract on Brain Injury Caused by Nicotine in Male Rats

Table 4

Grading of necrosis and gliosis in brain tissue.

	Score		C	T1	T2	T3	T4	T5
Neuron necrosis	Not seen	0	0	0	0	3	2	3
	Less than 25%	1
	Between 25 and 50%	2
	Between 50 and 75%	3
	More than 75%	4
Gliosis	Not seen	0	0	0	0	0	0	1
	Focal and less than 25%	1
	Focal and between 25 and 50%	2
	Focal but severe	3
	Severe and diffuse	4
Total score		0–8	0	0	0	3	2	4