Network Pharmacology and Molecular Docking-Based Analysis on Bioactive Anticoronary Heart Disease Compounds in Trichosanthes kirilowii Maxim and Bulbus allii Macrostemi

Figure 4

Components with the highest affinity in the molecular docking analysis. (a) Interleukin 6 and quercetin, affinity = −6.3 kcal/mol. (b) Tumour necrosis factor and β-sitosterol, affinity = −8.3 kcal/mol. (c) Prostaglandin-endoperoxide synthase 2 and quercetin, affinity = −9.7 kcal/mol. (d) B-cell leukaemia/lymphoma 2 and β-sitosterol, affinity = −7.6 kcal/mol. (e) Nitric oxide synthase 3 and β-sitosterol, affinity = −9 kcal/mol. (f) Vascular cell adhesion molecule-1 and naringenin, affinity = −6.6 kcal/mol. Solid blue lines represent hydrogen bonds, while dotted grey lines represent hydrophobic interactions.

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(b)

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