PEI-PEG-Coated Mesoporous Silica Nanoparticles Enhance the Antitumor Activity of Tanshinone IIA and Serve as a Gene Transfer Vector

<div>Identification of GPC3-shRNA plasmids and MSN-PEG. (a) GPC3-shRNA sequencing comparison results. (b–d). Binding, digestion, and release of MSN-PEG with GPC3-shRNA plasmid. (b) Electrophoresis image of MSN-PEG with various mass ratios after binding with GPC3-shRNA plasmids. (c) Electrophoresis image of the release experiment of MSN-PEG/GPC3-shRNA complex. (d) Electrophoresis image of the digestion protection experiment of MSN-PEG/GPC3-shRNA complex.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 4

Figure 4: PEI-PEG-Coated Mesoporous Silica Nanoparticles Enhance the Antitumor Activity of Tanshinone IIA and Serve as a Gene Transfer Vector 