A Novel Supplement Attenuates Oxidative Stress-Induced TDP-43-Related Pathogenesis in TDP-43-Expressed Cells

Figure 2

SA-induced cell death from BJIGT combined with riluzole in TDP-43-expressed stress granular cells. TDP-43 stress granular cells were pretreated with BJIGT (100 μg/mL), riluzole (50 μM), and combined BJIGT (100 μg/mL)/riluzole (50 μM) for 6 h before treatment of SA (150 μM) for 18 h. Combined treatment prevented SA-induced cell death in TDP-43 stress granular cells. SA, sodium arsenite; BJIGT, Bojungikgi-tang; RI, riluzole.