A Novel Supplement Attenuates Oxidative Stress-Induced TDP-43-Related Pathogenesis in TDP-43-Expressed Cells

Figure 5

Autophagy function effects of BJIGT combined with riluzole in TDP-43-expressed stress granular cells. Cell lysates were used to detect P62, LC3b, and ATG7 expression by Western blots. Combined treatment reduced SA-induced autophagy dysfunction in TDP-43 stress granular cells. (a) Representative data of autophagy-related protein expressions (P62, LC3b, and ATG7) in TDP-43 stress granular cells. Tubulin was used as loading control. (b) Quantification of immunoblots. Bars show the means ± SEMs of more than three independent experiments. vs. the SA-treated control group.

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