Poria cocos Regulates Cell Migration and Actin Filament Aggregation in B35 and C6 Cells by Modulating the RhoA, CDC42, and Rho Signaling Pathways

Figure 2

Poria cocos induced activation of RhoA and CDC42 in B35 and C6 cells. The expression levels of activated RhoA, CDC42, and Rac1 were examined using western blotting in this experiment. B35 (a, b) and C6 (c, d) cells were treated with PRP (10 μg/ml) or WP (10 μg/ml). The GTP form of Rho protein was pulled down and analyzed. The bar charts were calculated based on triplicate western blot data from three batches of PRP- or WP-treated cells using Student’s t-test (; ). C/CTRL: control; PRP: Poria cocos cum Radix Pini; WP: White Poria.

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