Andrographolide Inhibition of Th17-Regulated Cytokines and JAK1/STAT3 Signaling in OVA-Stimulated Asthma in Mice

<table class="table-group" id="tab1"><tr><td><table class="table"><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr class="thead"><td class="align_left">Primers</td><td class="align_center">Sequences (5′to3′)</td></tr><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr><td class="align_left">Mouse ROR<i>α</i> forward</td><td class="align_center">GTGGAGACAAATCGTCAGGAAT</td></tr><tr><td class="align_left">Mouse ROR<i>α</i> reverse</td><td class="align_center">TGGTCCGATCAATCAAACAGTTC</td></tr><tr><td class="align_left">Mouse ROR<i>γ</i>t forward</td><td class="align_center">GAAGGCAAATACGGTGGTGT</td></tr><tr><td class="align_left">Mouse ROR<i>γ</i>t reverse</td><td class="align_center">AGAGGGCAATCTCATCCTCA</td></tr><tr><td class="align_left">Mouse <i>ß</i>-actin forward</td><td class="align_center">CATCCGTAAAGACCTCTATGCCAAC</td></tr><tr><td class="align_left">Mouse <i>ß</i>-actin reverse</td><td class="align_center">ATGGAGCCACCGATCCACA</td></tr><tr class="table-tr"><td colspan="2"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>AG inhibits the mRNA expression of RORγt. The PCR primer of mRNA is shown.</div>

Evidence-Based Complementary and Alternative Medicine

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Table 1

Table 1: Andrographolide Inhibition of Th17-Regulated Cytokines and JAK1/STAT3 Signaling in OVA-Stimulated Asthma in Mice 