Zisheng Shenqi Decoction Ameliorates Monosodium Urate-Mediated Gouty Arthritis in Rats via Promotion of Autophagy through the AMPK/mTOR Signaling Pathway

<div>ZSD increased antioxidant status and suppressed oxidative stress in the GA rat model. ((a)–(e)) The activities of GSH-Px, SOD, and CAT, and contents of MDA and NO in serum of rats were determined using corresponding kits. 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602Z"></path></g><g transform="matrix(.013,0,0,-0.013,61.846,0)"><path d="M384 0V27C293 34 287 42 287 114V635C232 613 172 594 109 583V559L157 557C201 555 205 550 205 499V114C205 42 199 34 109 27V0H384Z"></path></g></svg> compared with the MSU group. GSH-Px: glutathione peroxidase; SOD: superoxide dismutase; MDA: malondialdehyde; NO: nitrogen monoxide; CAT: catalase.</div>

Evidence-Based Complementary and Alternative Medicine

fig3

Figure 3

Figure 3: Zisheng Shenqi Decoction Ameliorates Monosodium Urate-Mediated Gouty Arthritis in Rats via Promotion of Autophagy through the AMPK/mTOR Signaling Pathway 

Figure 3 | Zisheng Shenqi Decoction Ameliorates Monosodium Urate-Mediated Gouty Arthritis in Rats via Promotion of Autophagy through the AMPK/mTOR Signaling Pathway 