Evaluation of the Antimalarial Activity of Crude Extract of Eucalyptus globulus Labill. Leaf against Plasmodium berghei in Mice

Table 2

Rectal temperature and bodyweight of infected mice treated with 80% methanol leaf extract of E. globulus in the 4-day suppressive test.

Groups	Body weight (g)			Rectal temperature (°C)
	D0	D4	% change	D0	D4	% change
DW	26.92 ± 0.83	22.50 ± 1.13	−16.58	37.25 ± 0.21	34.33 ± 0.42	−7.84
CE (mg/kg)
100	27.67 ± 1.21	24.83 ± 1.15	−10.27^a1b3	36.75 ± 0.21	34.25 ± 0.21	−6.80^b3
200	27.58 ± 1.46	26.08 ± 1.36	−5.42^a3b3	36.67 ± 0.21	35.08 ± 0.35	−4.32^a2b3
400	26.92 ± 0.79	27.00 ± 0.62	0.41^a3b2	37.00 ± 0.29	35.67 ± 0.31	−4.96^a1b3
CQ25 mg/kg	27.33 ± 0.63	29.67 ± 0.76	8.54^a3	36.92 ± 0.30	37.25 ± 0.17	0.92^a3

Data are expressed as mean ± SEM; n = 6. DW = distilled water, CE = crude extract, CQ = chloroquine, D0 = day 0, D4 = day 4, a = compared to negative control, b = compared to a standard drug, 1 = , 2 = , and 3 = .