Evaluation of the Antimalarial Activity of Crude Extract of Eucalyptus globulus Labill. Leaf against Plasmodium berghei in Mice

Table 5

Rectal temperature and bodyweight of infected mice treated with 80% methanol leaf extract of E. globulus in Rane’s test.

Groups	Weight (Gram)			Rectal temperature (°C)
	D3	D7	% change	D3	D7	% change
DW	26.92 ± 0.83	22.8 ± 31.17	−15.37 ± 2.34	37.25 ± 0.21	34.50 ± 0.37	−7.39 ± 0.60
CE (mg/kg)
100	27.67 ± 1.21	25.5 ± 81.00	−7.43 ± 0.57^a2b3	36.75 ± 0.21	34.75 ± 0.17	−5.44 ± 0.48^b3
200	27.58 ± 1.46	25.3 ± 31.43	−8.24 ± 0.47^a2b3	36.67 ± 0.21	35.67 ± 0.31	−2.73 ± 0.50^a3b2
400	26.92 ± 0.79	27.17 ± 0.69	0.99 ± 0.62^a3b2	37.00 ± 0.29	36.42 ± 0.30	−1.58 ± 0.22^a3
CQ25 mg/kg	27.33 ± 0.63	29.42 ± 0.82	7.59 ± 1.26^a3	36.92 ± 0.30	36.92 ± 0.24	0.02 ± 0.61^a3

Data are expressed as mean ± SEM; n = 6. DW = distilled water, CE = crude extract, CQ = chloroquine, D3 = day 3, D7 = day 7, a = compared to negative control, b = compared to a standard drug, 1 = , 2 = , and 3 = .