Evaluation of the Antimalarial Activity of Crude Extract of Eucalyptus globulus Labill. Leaf against Plasmodium berghei in Mice

Table 8

Rectal temperature and bodyweight of P. berghei-infected mice treated with 80% methanol leaf extract of E. globulus in the prophylactic test.

Groups	Rectal temperature (°C)			Body weight (grams)
	D0	D7	% change	D0	D7	% change
DW	37.25 ± 0.21	33.17 ± 0.61	−10.99 ± 1.17	27.50 ± 0.58	21.75 ± 0.89	−21.00 ± 2.23
CE (mg/kg)
100	36.75 ± 0.21	33.67 ± 0.25	−8.38 ± 0.63^b3	27.58 ± 0.76	23.83 ± 0.87	−13.60 ± 2.22^a1b3
200	36.67 ± 0.21	34.58 ± 0.30	−5.69 ± 0.43^a3b3	27.83 ± 1.05	25.75 ± 1.14	−7.56 ± 1.47^a3b2
400	36.83 ± 0.21	35.42 ± 0.20	−3.84 ± 0.41^a3b2	26.83 ± 0.74	25.67 ± 0.68	−4.32 ± 0.75^a3b1
CQ 25 mg/kg	36.92 ± 0.30	37.00 ± 0.29	0.23 ± 0.54^a3	27.00 ± 0.34	27.75 ± 0.28	2.81 ± 0.80^a3

Data are expressed as mean ± SEM; n = 6. DW = distilled water, CE = crude extract, CQ = chloroquine, D0 = day 0, D7 = day 7, a = compared to negative control, b = compared to a standard drug, 1 = , 2 = , and 3 = .