Use of Network Pharmacology and Molecular Docking Technology to Analyze the Mechanism of Action of Velvet Antler in the Treatment of Postmenopausal Osteoporosis

Figure 7

The molecular docking model of the top three active ingredients in velvet antler and the eleven core targets. In the 3D diagram, the red dotted line indicates the hydrogen bonds and related residues connected to each other, and the text represents the name of the residue. (a) AKT1 and 17-beta-estradiol; (b) AKT1 and oestrone; (c) AKT1 and adenosine triphosphate; (d) IL6 and adenosine triphosphate; (e) EGFR and 17-beta-estradiol; (f) EGFR and oestrone; (g) ESR1 and 17-beta-estradiol; (h) ESR1 and oestrone; (i) SRC and 17-beta-estradiol; (j) SRC and oestrone; (k) SRC and adenosine triphosphate; (l) STAT3 and 17-beta-estradiol; (m) STAT3 and oestrone; (n) STAT3 and adenosine triphosphate; (o) TNF and adenosine triphosphate; (p) MAPK1 and 17-beta-estradiol; (q) MAPK1 and oestrone; (r) MAPK1 and adenosine triphosphate; (s) JUN and 17-beta-estradiol; (t) JUN and oestrone; (u) JUN and adenosine triphosphate.

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