Ethyl Acetate Fraction from Leandra dasytricha (A. Gray) Cong. Leaves Promotes Vasodilatation and Reduces Blood Pressure in Normotensive and Hypertensive Rats

Table 1

Chemical constituents from the ethyl acetate fraction (EAF) of L. dasytricha.

Peak	Compound	RT (min)	MF	UV (nm)	m/z		MS/MS
					[M + H]^+	[M-H]^-
1	Di-O-hexoside	1.1	C12H22O11	—	365.1044^Na	341.1028	—
2	Shikimic acid	1.2	C7H10O5	—	—	173.0459	—
3	Gallic acid^st	2.4	C7H6O5	270	—	169.0125	—
4	Castalagin isomer	4.5	C41H26O26	285	935.0803	466.0275^–2	466 ⟶ 301, 275, 231, 191, 169
5	Methyl gallate	7.8	C8H8O5	270	185.0444	183.0299	183 ⟶ 168
6	Catechin^st	9.1	C15H14O6	270	291.0855	289.0695	289 ⟶ 221, 203, 151
7	Acutissimin A/B isomer	9.7	C56H38O31	285	—	602.0626^–2	602 ⟶467, 301, 275, 249, 169
8	Tri-O-galloyl hexoside	15.6	C27H24O18	270	637.1035	635.089	635 ⟶ 465, 313, 423, 271, 211, 169
9	O-hexosyl phloretin	16.0	C21H24O10	284	437.1442	435.1297	435 ⟶ 255, 229
10	C-hexosyl hydroxyphlorizin	16.6	C21H24O11	284	453.1391	451.1246	451 ⟶ 361, 331, 239, 167
11	Ellagic acid^st	17.7	C14H6O8	282, 368	303.0120	300.9996	301 ⟶ 283, 257, 245, 229
12	Di-C-hexosyl phloretin	19.1	C27H34O15	286	599.1970	597.1825	597 ⟶ 417, 387, 357, 315, 209, 167
13	C-hexosyl phloretin (nothofagin)	19.4	C21H24O10	286	437.1442	435.1297	435 ⟶ 345, 315, 273, 209, 167
14	Unknown	20.8	C27H28O12	280	545.1654	543.1508	543 ⟶ 313, 229, 169
15	C-hexosyl phloretin	24.2	C21H24O10	285	437.1437	435.1293	435 ⟶ 345, 315, 272, 209, 179, 167
16	Tri-O-methyl ellagic acid	24.4	C17H12O8	285, 368	345.0605	343.0459	345 ⟶ 330, 315, 285
17	O-galloyl C-hexosyl phloretin	24.8	C28H28O14	284	589.1536	587.1412	587 ⟶ 345, 315, 273, 209, 167
18	O-acetyl C-hexosyl phloretin	25.6	C23H26O11	284	479.1525	477.1407	477 ⟶ 345, 315, 273, 167
19	Phloretin	28.4	C15H14O5	285	275.0914	273.0768	273 ⟶ 189, 167, 151
20	Triterpene	33.8	C30H48O5	—	489.3575	487.3429	—
21	Triterpene	34.6	C30H48O5	—	489.3564	487.3445	—

MF: molecular formula; RT: retention time; ^Na: [M+Na]⁺; ⁻²: [M-2H]⁻²; st: confirmed by authentic standard.