Research Article

Enteral Nutrition Combined with Improved-Sijunzi Decoction Shows Positive Effect in Precachexia Cancer Patients: A Retrospective Analysis

Table 4

Comparison of patients' blood indicators.

Blood indicatorTimeISJZ groupSEN group-value

RBC (10^12/L)Baseline3.54 ± 0.603.98 ± 0.690.004
Ending3.81 ± 0.583.55 ± 0.760.092
Difference0.21 (0.10, 0.45)−0.35 (−0.62, −0.18)0.0001

HGB (g/L)Baseline106.48 ± 16.47114.60 ± 20.360.051
Ending114.17 ± 17.43101.91 ± 20.500.006
Difference7.00 (2.00, 12.00)−10.00 (−20.00, −5.00)0.0001

PAlb (g/L)Baseline0.14 ± 0.050.14 ± 0.070.638
Ending0.19 ± 0.070.13 ± 0.070.001
Difference0.05 (0.02, 0.083)−0.02 (−0.07, 0.06)0.0001

Alb (g/L)Baseline32.63 ± 6.8935.44 ± 9.240.120
Ending36.22 ± 5.0430.24 ± 6.640.0001
Difference2.85 (0.70, 4.90)−2.6 ( 7.05, 0.13)0.0001

TP (g/L)Baseline61.15 ± 6.9666.76 ± 7.210.053
Ending67.13 ± 7.1562.06 ± 8.970.008
Difference4.95 (2.65, 7.68)−4.90 (−9.50, 3.50)0.0001

ChE (U/L)Baseline5671.21 ± 1708.044930.71 ± 2053.720.081
Ending6340.07 ± 1594.364776.43 ± 1893.460.0001
Difference576.50 (93.50, 890.50)61.00 (−2055.00, 827.00)0.043

CRP (mg/L)Baseline42.7537.800.535
Ending19.7538.100.081
Difference−10.27 (−45.99, 2.38)−3.00 (−41.60, 14.00)0.308

CRP/AlbBaseline1.32 (0.28, 2.69)0.96 (0.52, 2.94)0.696
Ending0.57 (0.14, 1.67)1.52 (0.41, 3.16)0.028
Difference−0.38 (−1.76, 0.014)0.045 (−0.92, 1.32)0.027

CRP/PAlbBaseline0.33 (0.07, 0.93)0.46 (0.10, 1.04)0.443
Ending0.11 (0.03, 0.34)0.38 (0.11, 0.94)0.005
Difference−0.14 (−0.58, −0.00)0.02 (−0.42, 0.37)0.032

WBC (10^9/L)Baseline7.40 ± 3.619.06 ± 4.370.065
Ending7.55 ± 3.458.21 ± 3.800.413
Difference0.56 (−0.33, 1.92)−0.80 (−2.24, 0.60)0.01

ALT (U/L)Baseline19.98 ± 15.3418.71 ± 14.600.709
Ending27.32 ± 17.4220.29 ± 16.060.066
Difference3.00 (−4.25, 18.75)1.00 (−13.00, 11.00)0.256

AST (U/L)Baseline24.54 ± 13.5830.60 ± 25.020.167
Ending29.54 ± 15.8132.86 ± 32.860.551
Difference2.50 (−3.50, 12.25)−2.00 (−14.00, 17.00)0.190

ALP (U/L)Baseline125.74 ± 76.38154.09 ± 114.330.185
Ending140.48 ± 79.65189.91 ± 206.490.141
Difference8.00 (−3.75, 24.50)3.00 (−64.00, 73.00)0.706

CREA (μmol/L)Baseline55.93 ± 11.9756.51 ± 16.770.856
Ending52.56 ± 11.8051.34 ± 16.630.704
Difference−1.00 (−7.5, 1.50)−5.00 (−24.00, 8.00)0.464

UREA (mmol/L)Baseline4.52 ± 1.486.36 ± 4.680.030
Ending4.97 ± 1.935.73 ± 2.390.116
Difference0.20 (−0.45, 1.00)−0.10 (−3.10, 1.70)0.167

Statistical significance at ; statistical significance at . Baseline and ending: mean ± SD; difference: median (p25, p50). RBC, red blood cell; HGB, hemoglobin; PAlb, prealbumin; Alb, albumin; TP, total protein; ChE, cholinesterase; CRP, C-reactive protein; WBC, leukocyte; ALT, alanine aminotransferase; AST, aspartate aminotransferase; ALP, alkaline phosphatase; CREA, creatinine; UREA, urea nitrogen.