Comparison of Pharmacokinetics and Tissue Distribution Characteristics of Three Diterpenoid Esters in Crude and Prepared Semen Euphorbiae

Table 2

Linear relationship of three analytes in tissue samples of mice.

Analytes	Tissue	Standard curve	r	Linear range (ng·mL^−1)	LOQ (ng·mL^−1)
Euphorbia factor L1	Heart	Y = 0.034618X + 0.00207128	0.9932	1.002–801.6	1.002
	Liver	Y = 0.00977173X + 0.00916433	0.9990
	Spleen	Y = 0.117309X + 0.00187417	0.9980
	Lung	Y = 0.0817354X + 0.0872459	0.9976
	Kidney	Y = 0.00450416X + 0.000260721	0.9987
	Colon	Y = 0.0349301X + 0.022299	0.9976
Euphorbia factor L2	Heart	Y = 0.400486X + 0.23513	0.9978	1.010–808.0	1.010
	Liver	Y = 0.188429X + 0.0965572	0.9935
	Spleen	Y = 1.0453X−0.17471	0.9955
	Lung	Y = 0.502219X + 0.344347	0.9980
	Kidney	Y = 0.294794X + 0.2747	0.9922
	Colon	Y = 0.313598X + 0.332799	0.9924
Euphorbia factor L3	Heart	Y = 0.250723X + 0.120749	0.9959	1.002–801.6	1.002
	Liver	Y = 0.192895X + 0.0424932	0.9983
	Spleen	Y = 0.581293X−0.0697721	0.9985
	Lung	Y = 0.346932X + 0.11191	0.9953
	Kidney	Y = 0.207445X + 0.0897848	0.9970
	Colon	Y = 0.281536X + 0.176594	0.9979