Research Article

[Retracted] Expression of Tspan8 in Patients with Intrahepatic Cholangiocarcinoma and Its Relationship with Clinicopathological Features and Prognosis

Table 1

Relationship between Tspan8 protein expression and clinicopathological features of ICC patients (n,  ± s).

Clinicopathological featuresTotal number of cases (n = 100)Tspan8 protein
NegativePositiveχ2

Age
  ≥60 years old5422 (56.41)32 (52.46)0.1500.699
  <60 years old4617 (43.59)29 (47.54)

Gender
  Male5621 (53.85)35 (57.38)0.1200.729
  Female4418 (46.15)26 (42.62)

Preoperative CEA
  ≥5 ng/mL6716 (41.03)51 (83.61)19.509≤0.001
  <5 ng/mL3323 (58.97)10 (16.39)

Preoperative CA199
  ≥34 U/mL6926 (66.67)43 (70.49)0.1630.687
  <34 U/mL3113 (33.33)18 (29.51)

Tumor diameter
  <4 cm4516 (41.03)29 (47.54)0.4080.523
  ≥4 cm5523 (58.97)32 (52.46)

Degree of tumor differentiation
  Low differentiation409 (23.08)31 (50.82)7.6290.006
  Moderate and high differentiation6030 (76.92)30 (49.18)

Lymph node metastasis
  Yes3811 (28.21)27 (44.26)2.6030.107
  No6228 (71.79)34 (55.74)

TNM stage
  I + II stage4127 (69.23)14 (22.95)21.064≤0.001
  III + IV stage5912 (30.77)47 (77.05)

Vascular tumor thrombus
  Yes4018 (46.15)22 (36.07)1.0090.315
  No6021 (53.85)39 (63.93)

Smoking history
  Yes5820 (51.28)38 (62.30)1.1840.276
  No4219 (48.72)23 (37.70)

Drinking history
  Yes4616 (41.03)30 (49.18)0.6370.425
  No5423 (58.97)31 (50.82)