Research Article
[Retracted] Expression of Tspan8 in Patients with Intrahepatic Cholangiocarcinoma and Its Relationship with Clinicopathological Features and Prognosis
Table 1
Relationship between Tspan8 protein expression and clinicopathological features of ICC patients (
n,
±
s).
| Clinicopathological features | Total number of cases (n = 100) | Tspan8 protein | Negative | Positive | χ2 | |
| Age | ≥60 years old | 54 | 22 (56.41) | 32 (52.46) | 0.150 | 0.699 | <60 years old | 46 | 17 (43.59) | 29 (47.54) |
| Gender | Male | 56 | 21 (53.85) | 35 (57.38) | 0.120 | 0.729 | Female | 44 | 18 (46.15) | 26 (42.62) |
| Preoperative CEA | ≥5 ng/mL | 67 | 16 (41.03) | 51 (83.61) | 19.509 | ≤0.001 | <5 ng/mL | 33 | 23 (58.97) | 10 (16.39) |
| Preoperative CA199 | ≥34 U/mL | 69 | 26 (66.67) | 43 (70.49) | 0.163 | 0.687 | <34 U/mL | 31 | 13 (33.33) | 18 (29.51) |
| Tumor diameter | <4 cm | 45 | 16 (41.03) | 29 (47.54) | 0.408 | 0.523 | ≥4 cm | 55 | 23 (58.97) | 32 (52.46) |
| Degree of tumor differentiation | Low differentiation | 40 | 9 (23.08) | 31 (50.82) | 7.629 | 0.006 | Moderate and high differentiation | 60 | 30 (76.92) | 30 (49.18) |
| Lymph node metastasis | Yes | 38 | 11 (28.21) | 27 (44.26) | 2.603 | 0.107 | No | 62 | 28 (71.79) | 34 (55.74) |
| TNM stage | I + II stage | 41 | 27 (69.23) | 14 (22.95) | 21.064 | ≤0.001 | III + IV stage | 59 | 12 (30.77) | 47 (77.05) |
| Vascular tumor thrombus | Yes | 40 | 18 (46.15) | 22 (36.07) | 1.009 | 0.315 | No | 60 | 21 (53.85) | 39 (63.93) |
| Smoking history | Yes | 58 | 20 (51.28) | 38 (62.30) | 1.184 | 0.276 | No | 42 | 19 (48.72) | 23 (37.70) |
| Drinking history | Yes | 46 | 16 (41.03) | 30 (49.18) | 0.637 | 0.425 | No | 54 | 23 (58.97) | 31 (50.82) |
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