Based on Network Pharmacology to Explore the Potential Bioactive Compounds and Mechanisms of Zuojin Pill for the Treatment of Ulcerative Colitis

Table 1

Hub genes in the PPI network.

Gene name	Degree	Betweenness centrality	Closeness centrality
JUN	40	0.0866053	0.52765957
MAPK1	35	0.10522212	0.51239669
TNF	33	0.06737271	0.49206349
PIK3CA	32	0.09809998	0.49011858
RELA	31	0.04010596	0.50612245
AKT1	31	0.07469638	0.49011858
TP53	30	0.06701158	0.49011858
FOS	28	0.03619664	0.484375
SRC	27	0.05381998	0.496
IL6	27	0.05383839	0.484375
MAPK14	26	0.02930984	0.47328244
MAPK8	24	0.0236753	0.46096654
VEGFA	23	0.05077093	0.5
CTNNB1	22	0.03781139	0.46268657
EGFR	22	0.05992162	0.48627451
SP1	21	0.03912481	0.46441948
ESR1	21	0.00980253	0.47148289
CXCL8	21	0.06791767	0.44604317
MYC	20	0.00939055	0.46969697
IL1B	19	0.01687947	0.46441948
JAK2	19	0.01407263	0.45925926
IL2	18	0.00668683	0.45588235
IL4	17	0.01066433	0.44765343
SMAD3	17	0.01141516	0.43055556
STAT1	16	0.01339176	0.44927536
NR3C1	16	0.00783583	0.44765343