Phenolic Compounds of Propolis Alleviate Lipid Metabolism Disorder

Figure 2

Phenolic acids reduce intracellular lipid contents in L02 cells. Note. (1) The cells were treated with palmitic acid (PA) in the absence or presence of different doses of phenolic acids for 24 h. (A) Images of cells were captured by microscope at 400 × original magnification showing lipid accumulation in cells sustained by Oil Red O. (B) Lipid accumulation relative ratio. (2) 0.375% bull serum albumin (BSA) treatment is the control group; 300 μmol/L PA treatment is the model group; 300 μmol/L PA and 50 μmol/L fenofibric acid (FFBA) treatment is the positive control group. 300 μmol/L PA and various concentrations of phenolic compound treatment are drug treatment groups. Significant differences () from the control group are marked with ∗ and from the model group are marked with #. (3) CNA: cinnamic acid; CFA: caffeic acid; FRA: ferulic acid; IFRA: isoferulic acid; CMA: p-coumaric acid; MCNA: 4-methoxy cinnamic acid; DMCA: 3, 4-dimethoxy cinnamic acid; CDA: cinnamylideneacetic acid.

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