Research Article

Jintiange Capsule May Have a Positive Effect on Pain Relief and Functional Activity in Patients with Knee Osteoarthritis: A Meta-Analysis of Randomized Trials

Table 1

The basic characteristics of the included studies.

TrailSample size (T/C)Man/womanAge (y), mean ± SD or median (range)TCDuration (weeks)Main outcomes

Jian and Sheng [13]78 (39/39)30/4855.39 ± 8.38JTG capsulesAlendronate12①②
Yi and Huan [14]120 (60/60)0/12056 (48–60)JTG capsulesGlucosamine hydrochloride6①②
Jianli [15]102 (51/51)NR66.58 ± 6.23JTG capsulesGlucosamine hydrochloride6②③
Jiewei et al. [16]60 (30/30)19/4153.46 ± 5.74JTG capsulesEtocoxib12①③
Fang and Qing [17]80 (40/40)NR66.31 ± 5.67JTG capsulesGlucosamine sulfate12②④
Cunzhu and Xiaodong [18]120 (60/60)61/5961 (45–70)JTG capsules + CSodium hyaluronate5
Yuhong et al. [19]60 (30/30)27/3354.96 ± 10.55JTG capsules + CSodium hyaluronate24
Yiebi et al. [20]80 (40/40)NR52.0 ± 6.4JTG capsulesLoxoprofen sodium12
Zhilin [21]120 (60/60)NR72.6 ± 10.2JTG capsulesVoltaren4
Fang et al. [22]130 (65/65)47/8355.52 ± 5.43JTG capsulesDiclofenac sodium8①③
Yun et al. [23]83 (41/42)31/5244.9 ± 6.3JTG capsules + CMeloxicam12①②
Junlian and Pengcheng [24]90 (45/45)25/6568.63 (50–75)JTG capsulesAceclofenac12①③
Dahua et al. [25]90 (45/45)42/4859.8 ± 1.4JTG capsulesGlucosamine sulfate4
Dongwei [26]90 (45/45)41/4960.8 ± 7.1JTG capsulesPiroxicam12①④
Jinping at al. [27]98 (49/49)48/5056.9 ± 13.0JTG capsules + CNaproxen14
Guoyu [28]72 (36/36)38/3466 (60–86)JTG capsulesIbuprofen12
Jiangang et al. [29]60 (30/30)14/4661.57 ± 6.68JTG capsulesAceclofenac4①④
Jian et al. [30]60 (30/30)16/4456.85JTG capsulesVoltaren4
Yunzhao and Lin [31]100 (50/50)43/5762.2 (40–80)JTG capsulesGlucosamine hydrochloride12
Dongliang et al. [32]72 (36/36)23/4958.25 (44–75)JTG capsulesGlucosamine hydrochloride12③④
Tao et al. [33]61 (31/30)26/3551.3JTG capsulesGlucosamine hydrochloride12
Shuangli et al. [34]70 (35/35)27/4362.12 (42–71)JTG capsulesGlucosamine hydrochloride12①②

T: trial group; C: control group; NR: not reported; ①: the total effective rate; ②: the VAS score; ③: the WOMAC score; ④: the Lequesne score; ⑤: adverse events. Mean ± SD is mean, and median (range) is median.