Icariin and Icariside II Reciprocally Stimulate Osteogenesis and Inhibit Adipogenesis of Multipotential Stromal Cells through ERK Signaling

Figure 4

Adipocyte-like cell formation during adipogenesis of MSCs. (a–d) Oil red O staining (100×). (a) AS medium. (b) AS + ES (10 nM). (c) AS + icariin (1 µM). (d) AS + icariside II (1 µM). (e-f) Quantification of oil red O staining: (e) Icariin. (f) Icariside II. and vs. the AS group. Scale bar = 40 µM.