Aerobic Exercise Attenuates Pressure Overload-Induced Cardiac Dysfunction through Promoting Skeletal Muscle Microcirculation and Increasing Muscle Mass

Figure 2

Exercise mitigated cardiac structure and dysfunction in TAC-induced hypertensive mice. Cardiac LVIDs, LVIDd, and ejection fraction were detected by ultrasound; the respective pictures of cardiac ultrasound in CON, TAC, and TAE were shown (a), and the results of LVIDs, LVIDd, and ejection fraction were calculated (b, c), heart muscle cross-sectional area was determined by HE staining, five views of each section were chosen, and pictures were captured by light microscope at 400× magnification (d). Total area and the number of cell nuclear were examined by Leica Qwin Plus software, and the muscle cross-sectional area was calculated (e). CON: control, TAC: transverse aortic constriction, and TAE: transverse aortic constriction plus exercised. n = 6 per group. vs. CON; vs. CON; vs. TAC.

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