Aerobic Exercise Attenuates Pressure Overload-Induced Cardiac Dysfunction through Promoting Skeletal Muscle Microcirculation and Increasing Muscle Mass

Figure 3

Aerobic exercise augmented the number of skeletal muscle capillaries in TAC-induced hypertensive mice. Skeletal muscle capillaries were determined by immunostaining with anti-CD31 antibody, platelet endothelial cell adhesion molecule-1. The positive spots that the arrows indicated represented capillary (a). Five views of each section were chosen, and the number of capillaries were counted under the light microscope at 400× magnification and analyzed by independent t-test (b). CON: control, TAC: transverse aortic constriction, and TAE: transverse aortic constriction plus exercised. n = 6 per group. vs. CON; vs. TAC.

(a)

(b)